WHAT IS TOURETTE?

CHILDREN HIT HARDEST

Tourette impacts children at a particularly vulnerable age –sufferers typically experience their first tics on average between age 3 and 9. And the more the child tries to suppress a tic, the more severe and compulsive it becomes. The psychological and social effects are devastating.

Yet developing a safe treatment with few side effects remains a challenge. Tourette is a complex condition. As with many other neurosteroid and hormone conditions, it is severely aggravated by stress. Complex co-morbidities with other stress disorders are common: 86% of patients with Tourette have at least one additional behavioral or developmental disorder (Univ. California, San Francisco) – ranging from ADHD, OCD/B, inattention, hyperactivity, impulsivity and childhood conduct disorder – all of which could also be heavily impacted by Allopregnanolone, the same potent neurosteroid that plays a key role in PMDD.

TOURETTE: A DEVASTATING IMPACT ON CHILDREN

32%

of children with TS have considered suicide and/or self-harm.

63%

have felt discriminated against (incl. bullying, suspension, exclusion).

40%

are forced to miss school. (1)

With stress and comorbidities exacerbating the condition, and with conventional treatments presenting serious side effects, Tourette is unsurprisingly highly refractory:

59%

Of children and adolescents take prescription medication to manage TS

44%

of parents feel their child’s symptoms are not adequately controlled by existing medication.

29%

of children and adolescents have tried five or more different medications. (1)

1. 2018 Impact Survey, Tourette Association of America