ALLO is a potent neurosteroid produced in the brain during stress situations. 2017 preclinical research indicated that increased ALLO production during stress enhances tics(2). A further Asarina Pharma preclinical Tourette study in 2019 (3) went on to demonstrate that Sepranolone can reduce the negative effects of increased ALLO not only when it is produced peripherally (as with PMDD or MM) but when it is produced as a stress hormone in the brain of both genders during Tourette.
CEO Peter Nordkild